On location... Most vegetables require a great deal of sunlight, so your vegetable garden should be located where it will receive a minimum of six hours of sunlight per day. Deer preferences for plants vary by area, but locate the garden aware from the forest line (both for more sun and to prevent easy access for critters). If wildlife is a proiminent feature in your location, also consider a fence. For deer, eight feet or more is encouraged to discourage leaping.
On watering... Because your vegetables are outdoors and way from any overhangs, they may receive more natural rain water than your flower gardens. The general recommendation for vegetables is about one inch of water per week, whether it be from your hose or from the sky. Because rain amounts can vary, a soaker hose is encouraged to make it easier for you to control the amount of water your garden is receiving. It also can release a slow drip, which can have a better ability to soak deeply to the root system of the plant than overhead watering. Watering in the morning can help reduce the spread of diseases.
On feeding... Too much fertilizer can result in lots of lush greenery but not a lot of fruit - something a vegetable grower wants to avoid. Incorporate a well-aged compost into the soil about three weeks before planting. Up to 20% of the soil volume can be added as compost. A natural compost that has been well-aged can also be a great source of earthworms, which aerate the soil and make it healthier.
On pests... There's no magic bullet, but plants such as garlic, chrysanthemums, and marigolds are a natural pest deterent. Plant them around the borders of your garden to help discourage pests and critters from munching on your plants.